NYCPHP Meetup

[Rahmin Pavlovic]

I'm using my own Ajax API on a couple of our management systems.

It's fun.  You still need middleware for db connectivity -- and you'll
realistically need backup (ie, normal) solutions if you're not in a closed
environment -- but there's a ton of neat tricks you can do (especially if you
go more DHTML-heavy), so if you're willing to put in 3-4 times more 
development
time (by my estimates) to make sure all your initiatives are tight, then why
not.